REPORTER: It's the interview many have been waiting for. The cyclist is expected to confess to using performance enhancing drugs.
OPRAH WINFREY: "I would say he did not come clean in the manner that I expected. It was surprising to me. I would say that for myself, my team, all of us in the room, we were mesmerized and riveted by some of his answers."
REPORTER: Armstrong has always denied doping but this will be first time he addresses the issue since he was stripped of his seven Tour De France titles last year.
OPRAH WINFREY: "I think the most important questions and the answers that people around the world had been waiting to hear were answered and certainly answered."
REPORTER: A cancer survivor who went on to win cycling top prize, Armstrong's story made him a hero far beyond the world of sports. In the wake of a US Anti-doping Agency report last year, which described as the ringleader of a highly sophisticated doping ring, the once-revered cyclist has become a cautionary tale about the extent athletes will go to in order to win. His interview will air on Winfrey's OWN network on Thursday.