After years of often-breathless speculation about her future, Hillary Rodham Clinton confirmed one of the worst-kept secrets in politics: She’s running for president. The former first lady and secretary of state officially entered the 2016 presidential race with a video announcement to supporters Sunday, saying she wants to be the champion of “everyday Americans.” Read more >>
The cartoon by Bruce Plante, staff cartoonist for the Tulsa World, shows Hillary setting out on the campaign trail, suitcase in hand (NH stands for New Hampshire, by the way). Her husband Bill, who is wearing only a pair of boxer shorts with a heart motif, waves her off with the words, "Don't do anything I wouldn't do.", which leaves Hillary looking perplexed.
"Don't do anything I wouldn't do" is a humorous expression sometimes said to a person who is going on a journey. Literally, it means that if the person saying this would find an action improper/immoral, then you should not do it either. Their advice is to behave yourself. However, the statement can be used with sexual connotations, and in the cartoon there's clearly a reference to husband Bill's sex scandals, top of which is the Monica Lewinsky affair.
The Cagle Post has a good collection of cartoons about Hillary's decision to run for president.